The company’s AOC material (Alkylene Oxide Copolymer) is a water-soluble implantable biomaterial with a unique combination of properties:
- AOC dissolves and is eliminated from the body unchanged without any metabolic processes in 24 - 48 hours.
- AOC is non-inflammatory unlike resorbable polymers that must be broken down by metabolic or inflammatory processes.
- AOC does not swell as it dissolves. It does not compress surrounding structures or disperse particulate material that may be included within the implant.
- AOC is malleable and can be formulated to have a variety of handling characteristics that vary in consistency from a soft grease to a hard wax. This makes the polymer ideally suited for a wide range of medical applications.
- AOC can be formulated not to contain water, so that it can serve as a carrier for compounds, such as proteins, that are not stable in an aqueous solution.
Currently FDA Approved Applications for AOC Polymer
1) AOC as a bone hemostasis material is indicated for use as a water-soluble implant material and for use in the control of bleeding from cut bone surfaces.
Approved claims include:
· Does not interfere with bone healing
· Does not increase infection rates
· Non-inflammatory
2) AOC as an implantable material (FDA Class II) indicated for use as a water-soluble material as an adjunct during the natural healing process.
Approved claims include:
· Non-swelling
· Lubricious
· Biodissolvable
3) AOC approved as a coating for porous polyethylene maxillofacial implants in the craniomaxillofacial skeleton.
Approved claims include:
· Reduces tissue grab
· Makes implants easier to insert into tissue pockets
· Minimizes the debris accumulation within the pores
· Allows for fibrovascular tissue ingrowth
4) AOC as synthetic ceramic bone grafts suspended in a matrix used in spine surgery (licensed technology).

A microscopic image of polymer crystals.
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